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Surgical Site Infection in Primary and Delayed Primary Wound Closure in Perforated Appendicitis
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Jalil Feizi    , Amin Mirzaei , Rasoul Mirfallah , Masoud Fasihi , Maryam Rahmaty , Aliashraf Mozafari * |
| medical university of ilam |
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Abstract: (2198 Views) |
Background and Objective: Appendicitis is an acute inflammation of the appendix that has a progressive course and may lead to perforation, which highlights the importance of removing it by surgery as soon as possible. Surgical site infection (SSI) can be reduced by controlling risk factors, such as smoking or diabetes, and using prevention methods, such as antibiotic administration and hair removal. In addition, SSI may be affected by primary closure (PC) or delayed primary wound closure (DPC). This study aimed to compare SSI between PC or DPC in patients with perforated appendicitis.
Materials and Methods: This retrospective cohort study was conducted on 120 patients with perforated appendicitis at Imam Khomeini Hospital, Ilam, Iran. All patients had undergone an open appendectomy. The occurrence of infection was compared in 60 patients with PC and 60 with DPC. Logistic regression analyses were performed to evaluate the effect of wound closure on SSI.
Results: The SSI rate was reported at 17% in the whole sample, and 10% and 23% in the DPC and PC groups, respectively. In the multivariate logistic model, there was an 11.55-fold odds ratio of SSI for PC than for DPC. Moreover, a history of diabetes and high values of body mass index (BMI) showed a significant relationship with wound infection.
Conclusion: DPC is optimal compared to the PC technique for wound management in the case of perforated appendicitis. In addition, patients with a high BMI and a history of diabetes may be at higher risk for acquiring wound infections; therefore, it is essential that these patients carefully monitor their wounds.
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| Keywords: Appendicitis, Perforated, Surgical site infection, Wound closure technique |
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Full-Text [PDF 960 kb]
(561 Downloads)
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Type of Study: Applied research |
Subject:
Special
Received: 2022/12/4 | Accepted: 2023/01/21 | Published: 2023/03/21
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